HELPFUL SUPPORT FOR STARTING Corlanor^® TO TREAT YOUR CHRONIC HEART FAILURE

Important Safety Information

What is the most important information I should know about Corlanor^®? Corlanor^® may cause serious side effects, including:

• Harm to an unborn baby. Females who are able to get pregnant must use effective birth control during treatment with Corlanor^®. Tell your doctor right away if you become pregnant during treatment with Corlanor^®.
• Increased risk of irregular or rapid heartbeat (atrial fibrillation or heart rhythm problems). Tell your doctor if you feel any of the following symptoms of an irregular or rapid heartbeat: heart is pounding or racing (palpitations), chest pressure, worsened shortness of breath, near fainting or fainting.
• Slower than normal heart rate (bradycardia). Tell your doctor if you have a slowing of heart rate, or symptoms of a slow heart rate such as dizziness, fatigue, lack of energy.

• symptoms of heart failure that recently worsened
• very low blood pressure (hypotension)
• certain heart conditions: sick sinus syndrome, sinoatrial block, or 3rd-degree atrioventricular block
• a slow resting heart rate before treatment with Corlanor®. Ask your doctor what a slow resting heart rate is for you.
• certain liver problems
• been prescribed any medicines that can increase the effects of Corlanor^®.

Ask your doctor if you are not sure if you have any of the medical conditions listed above.

What should I tell my doctor before taking Corlanor^®? Before you take Corlanor^®, tell your doctor about all of your medical conditions, including if you:

• have any other heart problems, including heart rhythm problems, a slow heart rate, or a heart conduction problem.
• are breastfeeding or planning to breastfeed. It is not known if Corlanor^® passes into breast milk. You and your doctor should decide if you will take Corlanor^® or breastfeed; do not do both.
• are pregnant or planning to become pregnant. See "What is the most important information I should know about Corlanor^®? – Harm to an unborn baby" section.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Corlanor^® may affect the way other medicines work, and other medicines may affect how Corlanor^® works. This could cause serious side effects.

What are the possible side effects of Corlanor^®?

Corlanor^® may cause serious side effects. See "What is the most important information I should know about Corlanor^®?"

The most common side effects of Corlanor^® are:

• increased blood pressure
• temporary brightness in part of your field of vision. This is usually caused by sudden changes in light (luminous phenomena). This brightness usually happens within the first 2 months of treatment with Corlanor^® and may go away during or after treatment with Corlanor^®. Be careful when driving or operating machinery where sudden changes in light can happen, especially when driving at night.

These are not all the side effects of Corlanor^®. Ask your doctor or pharmacist for more information. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see Full Prescribing Information and Medication Guide.

INDICATION

Corlanor^® is a prescription medicine used:

• to treat adults who have chronic (lasting a long time) heart failure, with symptoms, to reduce their risk of hospitalization for worsening heart failure.